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Call your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common. For best results, keep using the medication as directed.

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Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. When treating lupus or arthritis , hydroxychloroquine is usually given daily for several weeks or months. Talk with your doctor if your symptoms do not improve after 6 months of treatment. Seek emergency medical attention or call the Poison Help line at An overdose of hydroxychloroquine can be fatal, especially in children.

Hydroxychloroquine overdose must be treated quickly.

Hydroxychloroquine (Plaquenil®) Drug Information Sheet

You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose. Overdose symptoms may include drowsiness, vision changes, slow heart rate, chest pain, severe dizziness, seizure convulsions , or shallow breathing. Take the missed dose as soon as you remember.


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Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis.

How should this medicine be used?

Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. Every effort has been made to ensure that the information provided by on this page is accurate, up-to-date, and complete, but no guarantee is made to that effect.

Plaquenil Information : Hydroxychloroquine : Johns Hopkins Arthritis Center

Drug information contained herein may be time sensitive. The information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy.

For more information about hydroxychloroquine, or for questions that are specific to your situation, always consult your physician.


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Although we strive to maintain the accuracy of the information provided, we accept no legal responsibility for any errors or omissions. Always check with your own physician first. This website is intended for a Canadian audience. DMARDs are a slow acting but effective treatment for rheumatoid arthritis and other forms of inflammatory arthritis. They are useful for early and mild cases of inflammatory arthritis.

Another common use is in the treatment of some forms of lupus and other connective tissue diseases. What is the typical dose?


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Chloroquine — Usually mg per day. How do anti-malarials work? This medicine should be taken with food or milk.

Prescriptions Management

When you are taking Hydroxychloroquine, it is very important that your doctors know if you are taking any other medicine. This includes prescription and non-prescription medicines as well as birth control pills, vitamins, and herbal supplements.

A Potential Cure for Coronavirus? FDA approves clinical trial of hydroxychloroquine for COVID-19!

Rarely, Hydroxychloroquine can cause vision problems. Your doctor may want you to have an eye exam before beginning this medication. You will then have an eye exam yearly with an ophthalmologist to check for any changes in the back of the eye. Notify your doctor if you experience any blurred vision or see black spots.